Copetran was founded in 1942 in Bucaramanga. It was a corporation of 3 bus owners. The governor of the province Dr. Arturo Santos has supported by one of the company to what was controlled by the government. The first trip was from Bucaramanga to Bogota in a bus with wooden seats and 20 people. In the front of the bus sat 2 jerry can with petrol for the trip of 24 hours.
The route network of currently around 100 destinations in Colombia. The current buses are from 2007 and have 2 toilets, LCD television with DVD and air conditioning and capacity for 2 drivers.